NEWS

Scientists Create ‘Anti-Fat’ Vaccine

A groundbreaking weekly injection may help prevent weight gain by reducing harmful inflammation, according to researchers at the University of Colorado.

Scientists tested the vaccine, made from Mycobacterium vaccae—a beneficial bacteria found in cow’s milk and soil—on mice. The vaccinated mice remained resistant to weight gain, even when fed a diet high in sugar and fat. Remarkably, their weight gain and visceral fat levels were similar to those of unvaccinated mice on a healthy diet.

The study, published in Brain, Behavior, and Immunity, suggests the vaccine combats stress-induced inflammation caused by inflammatory foods like processed meats, refined grains, and sugary drinks. Inflammation, along with high-calorie diets, raises cortisol levels, promoting fat storage. It also disrupts leptin, a hormone that regulates appetite and metabolism, potentially increasing hunger.

Lead researcher Dr. Christopher Lowry highlighted that the vaccine completely prevented weight gain in mice consuming an unhealthy diet. This discovery points to the potential for beneficial bacteria to offset some harmful effects of Western diets.

In the study, one group of mice ate regular rodent food without the vaccine, while another was fed a high-fat, high-sugar diet. Among the latter, half received weekly vaccine injections. After 10 weeks, unvaccinated mice on the unhealthy diet gained 16% more weight and had significantly more visceral fat than those on healthy diets. Vaccinated mice on the same unhealthy diet, however, showed no additional weight gain or increase in visceral fat.

While the results are promising, researchers caution that further studies are needed to determine whether the vaccine would produce similar effects in humans, as well as its potential cost and accessibility.

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